Cooperative Interaction between Phosphorylation Sites on PERIOD Maintains Circadian Period in Drosophila

Circadian rhythms in Drosophila rely on cyclic regulation of the period (per) and timeless (tim) clock genes. The molecular cycle requires rhythmic phosphorylation of PER and TIM proteins, which is mediated by several kinases and phosphatases such as Protein Phosphatase-2A (PP2A) and Protein Phospha...

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Detalles Bibliográficos
Autores principales: Garbe, David S., Fang, Yanshan, Zheng, Xiangzhong, Sowcik, Mallory, Anjum, Rana, Gygi, Steven P., Sehgal, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784489/
https://www.ncbi.nlm.nih.gov/pubmed/24086144
http://dx.doi.org/10.1371/journal.pgen.1003749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784489/
https://www.ncbi.nlm.nih.gov/pubmed/24086144
http://dx.doi.org/10.1371/journal.pgen.1003749

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