IL-17 Attenuates Degradation of ARE-mRNAs by Changing the Cooperation between AU-Binding Proteins and microRNA16

Interleukin 17A (IL-17), a mediator implicated in chronic and severe inflammatory diseases, enhances the production of pro-inflammatory mediators by attenuating decay of the encoding mRNAs. The decay of many of these mRNAs depends on proteins (AUBps) that target AU-rich elements in the 3′-untranslat...

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Detalles Bibliográficos
Autores principales: Chowdhury, Saheli, Dijkhuis, Annemiek, Steiert, Sabrina, Lutter, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784493/
https://www.ncbi.nlm.nih.gov/pubmed/24086143
http://dx.doi.org/10.1371/journal.pgen.1003747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784493/
https://www.ncbi.nlm.nih.gov/pubmed/24086143
http://dx.doi.org/10.1371/journal.pgen.1003747

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