Binding of NF-κB to Nucleosomes: Effect of Translational Positioning, Nucleosome Remodeling and Linker Histone H1

NF-κB is a key transcription factor regulating the expression of inflammatory responsive genes. How NF-κB binds to naked DNA templates is well documented, but how it interacts with chromatin is far from being clear. Here we used a combination of UV laser footprinting, hydroxyl footprinting and elect...

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Detalles Bibliográficos
Autores principales: Lone, Imtiaz Nisar, Shukla, Manu Shubhdarshan, Charles Richard, John Lalith, Peshev, Zahary Yordanov, Dimitrov, Stefan, Angelov, Dimitar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784511/
https://www.ncbi.nlm.nih.gov/pubmed/24086160
http://dx.doi.org/10.1371/journal.pgen.1003830