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In Vivo Analysis of Lrig Genes Reveals Redundant and Independent Functions in the Inner Ear
Lrig proteins are conserved transmembrane proteins that modulate a variety of signaling pathways from worm to humans. In mammals, there are three family members – Lrig1, Lrig2, and Lrig3 – that are defined by closely related extracellular domains with a similar arrangement of leucine rich repeats an...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784559/ https://www.ncbi.nlm.nih.gov/pubmed/24086156 http://dx.doi.org/10.1371/journal.pgen.1003824 |