Widespread Dysregulation of Peptide Hormone Release in Mice Lacking Adaptor Protein AP-3

The regulated secretion of peptide hormones, neural peptides and many growth factors depends on their sorting into large dense core vesicles (LDCVs) capable of regulated exocytosis. LDCVs form at the trans-Golgi network, but the mechanisms that sort proteins to this regulated secretory pathway and t...

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Detalles Bibliográficos
Autores principales: Sirkis, Daniel W., Edwards, Robert H., Asensio, Cédric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784564/
https://www.ncbi.nlm.nih.gov/pubmed/24086151
http://dx.doi.org/10.1371/journal.pgen.1003812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784564/
https://www.ncbi.nlm.nih.gov/pubmed/24086151
http://dx.doi.org/10.1371/journal.pgen.1003812

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