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Widespread Dysregulation of Peptide Hormone Release in Mice Lacking Adaptor Protein AP-3
The regulated secretion of peptide hormones, neural peptides and many growth factors depends on their sorting into large dense core vesicles (LDCVs) capable of regulated exocytosis. LDCVs form at the trans-Golgi network, but the mechanisms that sort proteins to this regulated secretory pathway and t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784564/ https://www.ncbi.nlm.nih.gov/pubmed/24086151 http://dx.doi.org/10.1371/journal.pgen.1003812 |