Steady-State Metabolite Concentrations Reflect a Balance between Maximizing Enzyme Efficiency and Minimizing Total Metabolite Load

Steady-state metabolite concentrations in a microorganism typically span several orders of magnitude. The underlying principles governing these concentrations remain poorly understood. Here, we hypothesize that observed variation can be explained in terms of a compromise between factors that favor m...

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Detalles Bibliográficos
Autores principales: Tepper, Naama, Noor, Elad, Amador-Noguez, Daniel, Haraldsdóttir, Hulda S., Milo, Ron, Rabinowitz, Josh, Liebermeister, Wolfram, Shlomi, Tomer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784570/
https://www.ncbi.nlm.nih.gov/pubmed/24086517
http://dx.doi.org/10.1371/journal.pone.0075370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784570/
https://www.ncbi.nlm.nih.gov/pubmed/24086517
http://dx.doi.org/10.1371/journal.pone.0075370

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