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MGMT Leu84Phe Polymorphism Contributes to Cancer Susceptibility: Evidence from 44 Case-Control Studies

BACKGROUND: O(6)-methylguanine-DNA methyltransferase is one of the few proteins to directly remove alkylating agents in the human DNA direct reversal repair pathway. A large number of case-control studies have been conducted to explore the association between MGMT Leu84Phe polymorphism and cancer ri...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Zhang, Renxia, Chen, Fei, Yu, Cuicui, Sun, Yan, Jia, Chuanliang, Zhang, Lijing, Salahuddin, Taufiq, Li, Xiaodong, Lang, Juntian, Song, Xicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784571/
https://www.ncbi.nlm.nih.gov/pubmed/24086516
http://dx.doi.org/10.1371/journal.pone.0075367