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Metformin Inhibits Follicle-Stimulating Hormone (FSH) Action in Human Granulosa Cells: Relevance to Polycystic Ovary Syndrome

BACKGROUND: Women with anovulatory polycystic ovary syndrome (PCOS) are generally insulin-resistant and as a consequence are often treated with the biguanide metformin. Results with metformin have, however, been variable with some studies demonstrating induction of regular cycles and an increase in...

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Detalles Bibliográficos
Autores principales: Rice, Suman, Elia, Androulla, Jawad, Zara, Pellatt, Laura, Mason, Helen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784648/
https://www.ncbi.nlm.nih.gov/pubmed/23846817
http://dx.doi.org/10.1210/jc.2013-1865