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The Solution Structure of Heparan Sulfate Differs from That of Heparin: IMPLICATIONS FOR FUNCTION

The highly sulfated polysaccharides heparin and heparan sulfate (HS) play key roles in the regulation of physiological and pathophysiological processes. Despite its importance, no molecular structures of free HS have been reported up to now. By combining analytical ultracentrifugation, small angle x...

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Detalles Bibliográficos
Autores principales: Khan, Sanaullah, Rodriguez, Elizabeth, Patel, Rima, Gor, Jayesh, Mulloy, Barbara, Perkins, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784691/
https://www.ncbi.nlm.nih.gov/pubmed/23921391
http://dx.doi.org/10.1074/jbc.M113.492223