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Opposing actions of environmental enrichment and Alzheimer's disease on the expression of hippocampal microRNAs in mouse models

Alzheimer's disease (AD) is the most common form of dementia in the elderly. Although there are no drugs that modify the disease process, exposure to an enriched environment (EE) can slow the disease progression. Here, we characterize the effects of AD and EE on the post-transcriptional regulat...

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Detalles Bibliográficos
Autores principales: Barak, B, Shvarts-Serebro, I, Modai, S, Gilam, A, Okun, E, Michaelson, D M, Mattson, M P, Shomron, N, Ashery, U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784766/
https://www.ncbi.nlm.nih.gov/pubmed/24022509
http://dx.doi.org/10.1038/tp.2013.77