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A novel and simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4(+) T cells in the hu-PBL SCID mice

Because dendritic cells (DCs) play a critical role in the regulation of adaptive immune responses, they have been ideal candidates for cell-based immunotherapy of cancers and infections in humans. Generally, monocyte-derived DCs (MDDCs) were generated from purified monocytes by multiple steps of tim...

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Detalles Bibliográficos
Autores principales: Kodama, Akira, Tanaka, Reiko, Saito, Mineki, Ansari, Aftab A., Tanaka, Yuetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784773/
https://www.ncbi.nlm.nih.gov/pubmed/24098298
http://dx.doi.org/10.3389/fmicb.2013.00292