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Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing

The tumor suppressor genes MGMT and DAPK1 become methylated in several cancers including diffuse large B-cell lymphoma (DLBCL). However, allelic methylation patterns have not been investigated in DLBCL. We developed a fast and cost-efficient method for the analysis of allelic methylation based on py...

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Detalles Bibliográficos
Autores principales: Kristensen, Lasse Sommer, Treppendahl, Marianne Bach, Asmar, Fazila, Girkov, Mia Seremet, Nielsen, Helene Myrtue, Kjeldsen, Tina Ellegaard, Ralfkiaer, Elisabeth, Hansen, Lise Lotte, Grønbæk, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784959/
https://www.ncbi.nlm.nih.gov/pubmed/24071855
http://dx.doi.org/10.1038/srep02789