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MUC5AC and inflammatory mediators associated with respiratory outcomes in the British 1946 birth cohort

Background and objective: Dysregulation of respiratory mucins, MUC5AC in particular, has been implicated in respiratory disease and MUC5AC expression is up-regulated in response to environmental challenges and inflammatory mediators. The aim of this study was to examine the effect of genetic variati...

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Detalles Bibliográficos
Autores principales: Johnson, Lauren, Shah, Imran, Loh, Andrew X, Vinall, Lynne E, Teixeira, Ana S, Rousseau, Karine, Holloway, John W, Hardy, Rebecca, Swallow, Dallas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784974/
https://www.ncbi.nlm.nih.gov/pubmed/23551418
http://dx.doi.org/10.1111/resp.12092