Structure of Active, Dimeric Human Telomerase

Telomerase contains a large RNA subunit TER and a protein catalytic subunit TERT. Whether telomerase functions as monomer or dimer has been a matter of debate. Here we report biochemical and labeling data that show that in vivo assembled human telomerase contains two TERT subunits and binds two telo...

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Detalles Bibliográficos
Autores principales: Sauerwald, Anselm, Sandin, Sara, Cristofari, Gaël, Scheres, Sjors H.W., Lingner, Joachim, Rhodes, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785136/
https://www.ncbi.nlm.nih.gov/pubmed/23474713
http://dx.doi.org/10.1038/nsmb.2530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785136/
https://www.ncbi.nlm.nih.gov/pubmed/23474713
http://dx.doi.org/10.1038/nsmb.2530

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