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Cerulenin Blockade of Fatty Acid Synthase Reverses Hepatic Steatosis in ob/ob Mice

Fatty liver or hepatic steatosis is a common health problem associated with abnormal liver function and increased susceptibility to ischemia/reperfusion injury. The objective of this study was to investigate the effect of the fatty acid synthase inhibitor cerulenin on hepatic function in steatotic o...

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Detalles Bibliográficos
Autores principales: Cheng, Gang, Palanisamy, Arun P., Evans, Zachary P., Sutter, Alton G., Jin, Lan, Singh, Inderjit, May, Harold, Schmidt, Michael G., Chavin, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785413/
https://www.ncbi.nlm.nih.gov/pubmed/24086674
http://dx.doi.org/10.1371/journal.pone.0075980