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SQSTM1/p62 Interacts with HDAC6 and Regulates Deacetylase Activity

Protein aggregates can form in the cytoplasm of the cell and are accumulated at aggresomes localized to the microtubule organizing center (MTOC) where they are subsequently degraded by autophagy. In this process, aggregates are engulfed into autophagosomes which subsequently fuse with lysosomes for...

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Detalles Bibliográficos
Autores principales: Yan, Jin, Seibenhener, Michael Lamar, Calderilla-Barbosa, Luis, Diaz-Meco, Maria-Theresa, Moscat, Jorge, Jiang, Jianxiong, Wooten, Marie W., Wooten, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785417/
https://www.ncbi.nlm.nih.gov/pubmed/24086678
http://dx.doi.org/10.1371/journal.pone.0076016