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microRNA-22 Promotes Heart Failure through Coordinate Suppression of PPAR/ERR-Nuclear Hormone Receptor Transcription

Increasing evidence suggests that microRNAs are intimately involved in the pathophysiology of heart failure. MicroRNA-22 (miR-22) is a muscle-enriched miRNA required for optimum cardiac gene transcription and adaptation to hemodynamic stress by pressure overload in mice. Recent evidence also suggest...

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Detalles Bibliográficos
Autores principales: Gurha, Priyatansh, Wang, Tiannan, Larimore, Ashley H., Sassi, Yassine, Abreu-Goodger, Cei, Ramirez, Maricela O., Reddy, Anilkumar K., Engelhardt, Stefan, Taffet, George E., Wehrens, Xander H. T., Entman, Mark L., Rodriguez, Antony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785418/
https://www.ncbi.nlm.nih.gov/pubmed/24086656
http://dx.doi.org/10.1371/journal.pone.0075882