Quantifying the Fitness Advantage of Polymerase Substitutions in Influenza A/H7N9 Viruses during Adaptation to Humans

Adaptation of zoonotic influenza viruses towards efficient human-to-human transmissibility is a substantial public health concern. The recently emerged A/H7N9 influenza viruses in China provide an opportunity for quantitative studies of host-adaptation, as human-adaptive substitutions in the PB2 gen...

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Detalles Bibliográficos
Autores principales: Fonville, Judith M., Burke, David F., Lewis, Nicola S., Katzelnick, Leah C., Russell, Colin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785442/
https://www.ncbi.nlm.nih.gov/pubmed/24086684
http://dx.doi.org/10.1371/journal.pone.0076047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785442/
https://www.ncbi.nlm.nih.gov/pubmed/24086684
http://dx.doi.org/10.1371/journal.pone.0076047

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