Modifications of Hippocampal Circuits and Early Disruption of Adult Neurogenesis in the Tg2576 Mouse Model of Alzheimer’s Disease

At advanced stages of Alzheimer’s disease, cognitive dysfunction is accompanied by severe alterations of hippocampal circuits that may largely underlie memory impairments. However, it is likely that anatomical remodeling in the hippocampus may start long before any cognitive alteration is detected....

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Detalles Bibliográficos
Autores principales: Krezymon, Alice, Richetin, Kevin, Halley, Hélène, Roybon, Laurent, Lassalle, Jean-Michel, Francès, Bernard, Verret, Laure, Rampon, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785457/
https://www.ncbi.nlm.nih.gov/pubmed/24086745
http://dx.doi.org/10.1371/journal.pone.0076497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785457/
https://www.ncbi.nlm.nih.gov/pubmed/24086745
http://dx.doi.org/10.1371/journal.pone.0076497

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