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Modifications of Hippocampal Circuits and Early Disruption of Adult Neurogenesis in the Tg2576 Mouse Model of Alzheimer’s Disease
At advanced stages of Alzheimer’s disease, cognitive dysfunction is accompanied by severe alterations of hippocampal circuits that may largely underlie memory impairments. However, it is likely that anatomical remodeling in the hippocampus may start long before any cognitive alteration is detected....
Autores principales: | Krezymon, Alice, Richetin, Kevin, Halley, Hélène, Roybon, Laurent, Lassalle, Jean-Michel, Francès, Bernard, Verret, Laure, Rampon, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785457/ https://www.ncbi.nlm.nih.gov/pubmed/24086745 http://dx.doi.org/10.1371/journal.pone.0076497 |
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