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Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

PURPOSE: To elucidate the role of biological and clinical impact of aberrant promoter hypermethylation (PH) in ovarian cancer (OC). EXPERIMENTAL DESIGN: PH of PGP9.5, HIC1, AIM1, APC, PAK3, MGMT, KIF1A, CCNA1, ESR1, SSBP2, GSTP1, FKBP4 and VGF were assessed by quantitative methylation specific PCR (...

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Detalles Bibliográficos
Autores principales: Brait, Mariana, Maldonado, Leonel, Noordhuis, Maartje, Begum, Shahnaz, Loyo, Myriam, Poeta, Maria Luana, Barbosa, Alvaro, Fazio, Vito M., Angioli, Roberto, Rabitti, Carla, Marchionni, Luigi, de Graeff, Pauline, J. van der Zee, Ate G., Wisman, G. Bea A., Sidransky, David, Hoque, Mohammad O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785492/
https://www.ncbi.nlm.nih.gov/pubmed/24086249
http://dx.doi.org/10.1371/journal.pone.0070878