A Low-Molecular-Weight Compound K7174 Represses Hepcidin: Possible Therapeutic Strategy against Anemia of Chronic Disease

Hepcidin is the principal iron regulatory hormone, controlling the systemic absorption and remobilization of iron from intracellular stores. The expression of the hepcidin gene, HAMP, is increased in patients with anemia of chronic disease. Previously, the synthetic compound K7174 was identified thr...

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Detalles Bibliográficos
Autores principales: Fujiwara, Tohru, Ikeda, Takashi, Nagasaka, Yuki, Okitsu, Yoko, Katsuoka, Yuna, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Ichinohasama, Ryo, Tomosugi, Naohisa, Harigae, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785497/
https://www.ncbi.nlm.nih.gov/pubmed/24086573
http://dx.doi.org/10.1371/journal.pone.0075568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785497/
https://www.ncbi.nlm.nih.gov/pubmed/24086573
http://dx.doi.org/10.1371/journal.pone.0075568

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