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Structural and Antigenic Variation among Diverse Clade 2 H5N1 Viruses

Antigenic variation among circulating H5N1 highly pathogenic avian influenza A viruses mandates the continuous production of strain-specific pre-pandemic vaccine candidates and represents a significant challenge for pandemic preparedness. Here we assessed the structural, antigenic and receptor-bindi...

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Detalles Bibliográficos
Autores principales: Shore, David A., Yang, Hua, Balish, Amanda L., Shepard, Samuel S., Carney, Paul J., Chang, Jessie C., Davis, Charles T., Donis, Ruben O., Villanueva, Julie M., Klimov, Alexander I., Stevens, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785507/
https://www.ncbi.nlm.nih.gov/pubmed/24086467
http://dx.doi.org/10.1371/journal.pone.0075209