Leptin Induces IL-6 Expression through OBRl Receptor Signaling Pathway in Human Synovial Fibroblasts

BACKGROUND: Leptin, an adipocyte-secreted hormone that centrally regulates weight control, may exert proinflammatory effects in the joint, depending on the immune response. Leptin is abundantly expressed in osteoarthritis (OA) cartilage and synovium. However, the relationship between leptin and inte...

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Detalles Bibliográficos
Autores principales: Yang, Wei-Hung, Liu, Shan-Chi, Tsai, Chun-Hao, Fong, Yi-Chin, Wang, Shoou-Jyi, Chang, Yung-Sen, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785513/
https://www.ncbi.nlm.nih.gov/pubmed/24086566
http://dx.doi.org/10.1371/journal.pone.0075551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785513/
https://www.ncbi.nlm.nih.gov/pubmed/24086566
http://dx.doi.org/10.1371/journal.pone.0075551

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