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A quantitative structure–activity relationship study of anti-HIV activity of substituted HEPT using nonlinear models

We performed studies on extended series of 79 HEPT ligands (1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine), inhibitors of HIV reverse-transcriptase with anti-HIV biological activity, using quantitative structure–activity relationship (QSAR) methods that imply analysis of correlations and represe...

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Detalles Bibliográficos
Autores principales: Noorizadeh, Hadi, Sajjadifar, Sami, Farmany, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785711/
https://www.ncbi.nlm.nih.gov/pubmed/24098069
http://dx.doi.org/10.1007/s00044-013-0525-4