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Cell and tissue polarity in the intestinal tract during tumourigenesis: cells still know the right way up, but tissue organization is lost

Cell and tissue polarity are tightly coupled and are vital for normal tissue homeostasis. Changes in cellular and tissue organization are common to even early stages of disease, particularly cancer. The digestive tract is the site of the second most common cause of cancer deaths in the developed wor...

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Detalles Bibliográficos
Autores principales: Fatehullah, Aliya, Appleton, Paul L., Näthke, Inke S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785964/
https://www.ncbi.nlm.nih.gov/pubmed/24062584
http://dx.doi.org/10.1098/rstb.2013.0014