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Expression of PIK3CA, PTEN mRNA and PIK3CA mutations in primary breast cancer: association with lymph node metastases

PURPOSE: High activity of the intracellular phosphatidylinositol-3 kinase (PI3K) pathway is common in breast cancer. Here, we explore differences in expression of important PI3K pathway regulators: the activator, phosphatidylinositol-3-kinase catalytic subunit alpha (PIK3CA), and the tumour suppress...

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Detalles Bibliográficos
Autores principales: Palimaru, Irina, Brügmann, Anja, Wium-Andersen, Marie Kim, Nexo, Ebba, Sorensen, Boe Sandahl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786083/
https://www.ncbi.nlm.nih.gov/pubmed/24083111
http://dx.doi.org/10.1186/2193-1801-2-464