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MAPKAP kinase 2 (MK2)-dependent and independent models of blister formation in pemphigus vulgaris

Pemphigus vulgaris (PV) is an autoimmune blistering disease characterized by autoantibodies to the keratinocyte adhesion protein desmoglein (Dsg) 3. Previous studies suggest that PV pathogenesis involves p38 mitogen activated protein kinase-dependent and -independent pathways. However, p38 is a diff...

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Detalles Bibliográficos
Autores principales: Mao, Xuming, Li, Hong, Sano, Yasuyo, Gaestel, Matthias, Park, Jin Mo, Payne, Aimee S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786199/
https://www.ncbi.nlm.nih.gov/pubmed/23657501
http://dx.doi.org/10.1038/jid.2013.224