Metabolic Characterization of a Sirt5 deficient mouse model

Sirt5, localized in the mitochondria, is a member of sirtuin family of NAD(+)-dependent deacetylases. Sirt5 was shown to deacetylate and activate carbamoyl phosphate synthase 1. Most recently, Sirt5 was reported to be the predominant protein desuccinylase and demalonylase in the mitochondria because...

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Detalles Bibliográficos
Autores principales: Yu, Jiujiu, Sadhukhan, Sushabhan, Noriega, Lilia G., Moullan, Norman, He, Bin, Weiss, Robert S., Lin, Hening, Schoonjans, Kristina, Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786297/
https://www.ncbi.nlm.nih.gov/pubmed/24076663
http://dx.doi.org/10.1038/srep02806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786297/
https://www.ncbi.nlm.nih.gov/pubmed/24076663
http://dx.doi.org/10.1038/srep02806

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