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Metabolic Characterization of a Sirt5 deficient mouse model
Sirt5, localized in the mitochondria, is a member of sirtuin family of NAD(+)-dependent deacetylases. Sirt5 was shown to deacetylate and activate carbamoyl phosphate synthase 1. Most recently, Sirt5 was reported to be the predominant protein desuccinylase and demalonylase in the mitochondria because...
Autores principales: | Yu, Jiujiu, Sadhukhan, Sushabhan, Noriega, Lilia G., Moullan, Norman, He, Bin, Weiss, Robert S., Lin, Hening, Schoonjans, Kristina, Auwerx, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786297/ https://www.ncbi.nlm.nih.gov/pubmed/24076663 http://dx.doi.org/10.1038/srep02806 |
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