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Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression

Proteins that interact with voltage-gated sodium (Na(v)) channels are important in channel sorting and modulation. In this study, we identified the transcriptional regulator, Sin3B, as a novel binding partner of Na(v) channels in a yeast two-hybrid screen and confirmed the interaction using pull-dow...

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Detalles Bibliográficos
Autores principales: Vega, Ana V., Avila, Guillermo, Matthews, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786298/
https://www.ncbi.nlm.nih.gov/pubmed/24077057
http://dx.doi.org/10.1038/srep02809