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A serotonin-induced N-glycan switch regulates platelet aggregation

Serotonin (5-HT) is a multifunctional signaling molecule that plays different roles in a concentration-dependent manner. We demonstrated that elevated levels of plasma 5-HT accelerate platelet aggregation resulting in a hypercoagulable state in which the platelet surface becomes occupied by several...

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Detalles Bibliográficos
Autores principales: Mercado, Charles P., Quintero, Maritza V., Li, Yicong, Singh, Preeti, Byrd, Alicia K., Talabnin, Krajang, Ishihara, Mayumi, Azadi, Parastoo, Rusch, Nancy J., Kuberan, Balagurunathan, Maroteaux, Luc, Kilic, Fusun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786303/
https://www.ncbi.nlm.nih.gov/pubmed/24077408
http://dx.doi.org/10.1038/srep02795