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A serotonin-induced N-glycan switch regulates platelet aggregation
Serotonin (5-HT) is a multifunctional signaling molecule that plays different roles in a concentration-dependent manner. We demonstrated that elevated levels of plasma 5-HT accelerate platelet aggregation resulting in a hypercoagulable state in which the platelet surface becomes occupied by several...
Autores principales: | Mercado, Charles P., Quintero, Maritza V., Li, Yicong, Singh, Preeti, Byrd, Alicia K., Talabnin, Krajang, Ishihara, Mayumi, Azadi, Parastoo, Rusch, Nancy J., Kuberan, Balagurunathan, Maroteaux, Luc, Kilic, Fusun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786303/ https://www.ncbi.nlm.nih.gov/pubmed/24077408 http://dx.doi.org/10.1038/srep02795 |
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