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Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes

INTRODUCTION: Tumors are characterized by alterations in the epithelial and stromal compartments, which both contribute to tumor promotion. However, where, when, and how the tumor stroma develops is still poorly understood. We previously demonstrated that DNA damage or telomere malfunction induces a...

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Detalles Bibliográficos
Autores principales: Fordyce, Colleen A, Patten, Kelley T, Fessenden, Tim B, DeFilippis, RosaAnna, Hwang, E Shelley, Zhao, Jianxin, Tlsty, Thea D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786321/
https://www.ncbi.nlm.nih.gov/pubmed/23216814
http://dx.doi.org/10.1186/bcr3368