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Inhibition of the group I mGluRs reduces acute brain damage and improves long-term histological outcomes after photothrombosis-induced ischaemia

Group I mGluRs (metabotropic glutamate receptors), including mGluR1 and mGluR5, are GPCRs (G-protein coupled receptors) and play important roles in physiology and pathology. Studies on their role in cerebral ischaemia have provided controversial results. In this study, we used a PT (photothrombosis)...

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Detalles Bibliográficos
Autores principales: Li, Hailong, Zhang, Nannan, Sun, Grace, Ding, Shinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786425/
https://www.ncbi.nlm.nih.gov/pubmed/23772679
http://dx.doi.org/10.1042/AN20130002