Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anti-cancer drug activity

Conventional anti-cancer drug screening is typically performed in the absence of accessory cells of the tumor microenvironment, which can profoundly alter anti-tumor drug activity. To address this major limitation, we developed the tumor cell-specific in vitro bioluminescence imaging (CS-BLI) assay....

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Detalles Bibliográficos
Autores principales: McMillin, Douglas W., Delmore, Jake, Weisberg, Ellen, Negri, Joseph M., Geer, D. Corey, Klippel, Steffen, Mitsiades, Nicholas, Schlossman, Robert L., Munshi, Nikhil C., Kung, Andrew L., Griffin, James D., Richardson, Paul G., Anderson, Kenneth C., Mitsiades, Constantine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786785/
https://www.ncbi.nlm.nih.gov/pubmed/20228816
http://dx.doi.org/10.1038/nm.2112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786785/
https://www.ncbi.nlm.nih.gov/pubmed/20228816
http://dx.doi.org/10.1038/nm.2112

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