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The Rho/Rho-associated protein kinase inhibitor fasudil in the protection of endothelial cells against advanced glycation end products through the nuclear factor κB pathway

Accumulating evidence has demonstrated that the Rho/Rho-associated protein kinase (Rho/ROCK) and nuclear factor κB (NF-κB) signaling pathways are involved in the pathogenesis of diabetic vascular injury. In this study, we investigated the beneficial effects of fasudil, a ROCK inhibitor, on vascular...

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Detalles Bibliográficos
Autores principales: LU, YUYAN, LI, HAILING, JIAN, WEIXIA, ZHUANG, JIANHUI, WANG, KE, PENG, WENHUI, XU, YAWEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786857/
https://www.ncbi.nlm.nih.gov/pubmed/24137180
http://dx.doi.org/10.3892/etm.2013.1125