An Updated Meta-Analysis on the Association of MDM2 SNP309 Polymorphism with Colorectal Cancer Risk

BACKGROUND: The mouse double minute 2 (MDM2) gene encodes a phosphoprotein that interacts with P53 and negatively regulates its activity. The SNP309 polymorphism (T-G) in the promoter of MDM2 gene has been reported to be associated with enhanced MDM2 expression and tumor development. Studies investi...

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Detalles Bibliográficos
Autores principales: Qin, Xue, Peng, Qiliu, Tang, Weizhong, Lao, Xianjun, Chen, Zhiping, Lai, Hao, Deng, Yan, Mo, Cuiju, Sui, Jingzhe, Wu, Junrong, Zhai, Limin, Yang, Shi, Li, Shan, Zhao, Jinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786895/
https://www.ncbi.nlm.nih.gov/pubmed/24098760
http://dx.doi.org/10.1371/journal.pone.0076031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786895/
https://www.ncbi.nlm.nih.gov/pubmed/24098760
http://dx.doi.org/10.1371/journal.pone.0076031

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