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Extracellular Acidic pH Inhibits Oligodendrocyte Precursor Viability, Migration, and Differentiation

Axon remyelination in the central nervous system requires oligodendrocytes that produce myelin. Failure of this repair process is characteristic of neurodegeneration in demyelinating diseases such as multiple sclerosis, and it remains unclear how the lesion microenvironment contributes to decreased...

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Detalles Bibliográficos
Autores principales: Jagielska, Anna, Wilhite, Kristen D., Van Vliet, Krystyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786906/
https://www.ncbi.nlm.nih.gov/pubmed/24098762
http://dx.doi.org/10.1371/journal.pone.0076048