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Panobinostat Synergistically Enhances the Cytotoxic Effects of Cisplatin, Doxorubicin or Etoposide on High-Risk Neuroblastoma Cells

High-risk neuroblastoma remains a therapeutic challenge with a long-term survival rate of less than 40%. Therefore, new agents are urgently needed to overcome chemotherapy resistance so as to improve the treatment outcome of this deadly disease. Histone deacetylase (HDAC) inhibitors (HDACIs) represe...

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Detalles Bibliográficos
Autores principales: Wang, Guan, Edwards, Holly, Caldwell, J. Timothy, Buck, Steven A., Qing, William Y., Taub, Jeffrey W., Ge, Yubin, Wang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786928/
https://www.ncbi.nlm.nih.gov/pubmed/24098799
http://dx.doi.org/10.1371/journal.pone.0076662