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The Uremic Toxin Indoxyl Sulphate Enhances Macrophage Response to LPS
Indoxyl sulphate (IS) is a protein-bound uremic toxin that results from the metabolism of dietary tryptophan normally excreted by kidney through the proximal tubules. Thus the toxin accumulates in the blood of patients with impaired renal function such as in chronic kidney disease (CKD). High IS ser...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786936/ https://www.ncbi.nlm.nih.gov/pubmed/24098806 http://dx.doi.org/10.1371/journal.pone.0076778 |