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The Uremic Toxin Indoxyl Sulphate Enhances Macrophage Response to LPS

Indoxyl sulphate (IS) is a protein-bound uremic toxin that results from the metabolism of dietary tryptophan normally excreted by kidney through the proximal tubules. Thus the toxin accumulates in the blood of patients with impaired renal function such as in chronic kidney disease (CKD). High IS ser...

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Detalles Bibliográficos
Autores principales: Adesso, Simona, Popolo, Ada, Bianco, Giuseppe, Sorrentino, Rosalinda, Pinto, Aldo, Autore, Giuseppina, Marzocco, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786936/
https://www.ncbi.nlm.nih.gov/pubmed/24098806
http://dx.doi.org/10.1371/journal.pone.0076778