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Are Interstitial Cells of Cajal Involved in Mechanical Stress-Induced Gene Expression and Impairment of Smooth Muscle Contractility in Bowel Obstruction?

BACKGROUND AND AIMS: The network of interstitial cells of Cajal (ICC) is altered in obstructive bowel disorders (OBD). However, whether alteration in ICC network is a cause or consequence of OBD remains unknown. This study tested the hypothesis that mechanical dilation in obstruction disrupts the IC...

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Detalles Bibliográficos
Autores principales: Wu, Chester C., Lin, You-Min, Gao, Jerry, Winston, John H., Cheng, Leo K., Shi, Xuan-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786942/
https://www.ncbi.nlm.nih.gov/pubmed/24098782
http://dx.doi.org/10.1371/journal.pone.0076222