Cargando…

Hypoxia Pathways and Cellular Stress Activate Pancreatic Stellate Cells: Development of an Organotypic Culture Model of Thick Slices of Normal Human Pancreas

Pancreatic stellate cells (PSC) are involved in fibrogenesis and oncogenesis by modulating the extracellular matrix. AIM: To evaluate the effect of cellular stress on PSC activation using a model of normal human pancreatic tissue slices culture preserving the microenvironment. METHODS: Thin sections...

Descripción completa

Detalles Bibliográficos
Autores principales: Rebours, Vinciane, Albuquerque, Miguel, Sauvanet, Alain, Ruszniewski, Philippe, Lévy, Philippe, Paradis, Valérie, Bedossa, Pierre, Couvelard, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786955/
https://www.ncbi.nlm.nih.gov/pubmed/24098783
http://dx.doi.org/10.1371/journal.pone.0076229