Cargando…

Relative Contributions of Norepinephrine and Serotonin Transporters to Antinociceptive Synergy between Monoamine Reuptake Inhibitors and Morphine in the Rat Formalin Model

Multimodal analgesia is designed to optimize pain relief by coadministering drugs with distinct mechanisms of action or by combining multiple pharmacologies within a single molecule. In clinical settings, combinations of monoamine reuptake inhibitors and opioid receptor agonists have been explored a...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Fei, Tsuruda, Pamela R., Smith, Jacqueline A. M., Obedencio, Glenmar P., Martin, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787017/
https://www.ncbi.nlm.nih.gov/pubmed/24098676
http://dx.doi.org/10.1371/journal.pone.0074891