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Loss of Fibrinogen in Zebrafish Results in Symptoms Consistent with Human Hypofibrinogenemia
Cessation of bleeding after trauma is a necessary evolutionary vertebrate adaption for survival. One of the major pathways regulating response to hemorrhage is the coagulation cascade, which ends with the cleavage of fibrinogen to form a stable clot. Patients with low or absent fibrinogen are at ris...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787019/ https://www.ncbi.nlm.nih.gov/pubmed/24098662 http://dx.doi.org/10.1371/journal.pone.0074682 |