MicroRNA-21-3p, a Berberine-Induced miRNA, Directly Down-Regulates Human Methionine Adenosyltransferases 2A and 2B and Inhibits Hepatoma Cell Growth

Methionine adenosyltransferase (MAT) is the cellular enzyme that catalyzes the synthesis of S-adenosylmethionine (SAM), the principal biological methyl donor and a key regulator of hepatocyte proliferation, death and differentiation. Two genes, MAT1A and MAT2A, encode 2 distinct catalytic MAT isofor...

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Detalles Bibliográficos
Autores principales: Lo, Ting-Fang, Tsai, Wei-Chung, Chen, Shui-Tein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787033/
https://www.ncbi.nlm.nih.gov/pubmed/24098708
http://dx.doi.org/10.1371/journal.pone.0075628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787033/
https://www.ncbi.nlm.nih.gov/pubmed/24098708
http://dx.doi.org/10.1371/journal.pone.0075628

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