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Live Attenuated Rev-Independent Nef¯SIV Enhances Acquisition of Heterologous SIVsmE660 in Acutely Vaccinated Rhesus Macaques

BACKGROUND: Rhesus macaques (RMs) inoculated with live-attenuated Rev-Independent Nef¯ simian immunodeficiency virus (Rev-Ind Nef¯SIV) as adults or neonates controlled viremia to undetectable levels and showed no signs of immunodeficiency over 6-8 years of follow-up. We tested the capacity of this l...

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Detalles Bibliográficos
Autores principales: Byrareddy, Siddappa N., Ayash-Rashkovsky, Mila, Kramer, Victor G., Lee, Sandra J., Correll, Mick, Novembre, Francis J., Villinger, Francois, Johnson, Welkin E., von Gegerfelt, Agneta, Felber, Barbara K., Ruprecht, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787041/
https://www.ncbi.nlm.nih.gov/pubmed/24098702
http://dx.doi.org/10.1371/journal.pone.0075556