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Blockade of the Formation of Insoluble Ubiquitinated Protein Aggregates by EGCG3”Me in the Alloxan-Induced Diabetic Kidney
BACKGROUND: Renal accumulation of reactive carbonyl compounds (RCCs) has been linked to the progression of diabetic nephropathy. We previously demonstrated that carbonyl stress induces the formation of amino-carbonyl cross-links and sharply increases the content of β-sheet-rich structures, which is...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787087/ https://www.ncbi.nlm.nih.gov/pubmed/24098713 http://dx.doi.org/10.1371/journal.pone.0075687 |