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Blockade of the Formation of Insoluble Ubiquitinated Protein Aggregates by EGCG3”Me in the Alloxan-Induced Diabetic Kidney

BACKGROUND: Renal accumulation of reactive carbonyl compounds (RCCs) has been linked to the progression of diabetic nephropathy. We previously demonstrated that carbonyl stress induces the formation of amino-carbonyl cross-links and sharply increases the content of β-sheet-rich structures, which is...

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Detalles Bibliográficos
Autores principales: Cai, Shuxian, Zhong, Yuan, Li, Yinhua, Huang, Jianan, Zhang, Jing, Luo, Guoan, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787087/
https://www.ncbi.nlm.nih.gov/pubmed/24098713
http://dx.doi.org/10.1371/journal.pone.0075687