A Purine Analog Synergizes with Chloroquine (CQ) by Targeting Plasmodium falciparum Hsp90 (PfHsp90)

BACKGROUND: Drug resistance, absence of an effective vaccine, and inadequate public health measures are major impediments to controlling Plasmodium falciparum malaria worldwide. The development of antimalarials to which resistance is less likely is paramount. To this end, we have exploited the chape...

Descripción completa

Detalles Bibliográficos
Autores principales: Shahinas, Dea, Folefoc, Asongna, Taldone, Tony, Chiosis, Gabriela, Crandall, Ian, Pillai, Dylan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787104/
https://www.ncbi.nlm.nih.gov/pubmed/24098696
http://dx.doi.org/10.1371/journal.pone.0075446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787104/
https://www.ncbi.nlm.nih.gov/pubmed/24098696
http://dx.doi.org/10.1371/journal.pone.0075446

Ejemplares similares